Arrestin-1 expression level in rods: balancing functional performance and photoreceptor health

In rod photoreceptors, signaling persists as long as rhodopsin remains catalytically active. Phosphorylation by rhodopsin kinase followed by arrestin-1 binding completely deactivates rhodopsin. Timely termination prevents excessive signaling and ensures rapid recovery. Mouse rods express arrestin-1...

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Hlavní autoři: Song, Xiufeng, Vishnivetskiy, Sergey A., Seo, Jungwon, Chen, Jeannie, Gurevich, Eugenia V., Gurevich, Vsevolod V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020241/
https://ncbi.nlm.nih.gov/pubmed/21075174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.11.009
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