Signal transduction and transforming properties of the TEL–TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia

The TEL–TRKC fusion is expressed as a consequence of t(12;15)(p13;q25), and is associated with two human cancers: congenital fibrosarcoma and acute myelogenous leukemia (AML). We report that the T/T(F) and T/T(L) fusion variants associated with congenital fibrosarcoma and AML, respectively, are cons...

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Главные авторы: Liu, Qing, Schwaller, Juerg, Kutok, Jeffery, Cain, Danielle, Aster, Jon C., Williams, Ifor R., Gilliland, D.Gary
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2000
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC302017/
https://ncbi.nlm.nih.gov/pubmed/10775267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.8.1827
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