Signal transduction and transforming properties of the TEL–TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia

The TEL–TRKC fusion is expressed as a consequence of t(12;15)(p13;q25), and is associated with two human cancers: congenital fibrosarcoma and acute myelogenous leukemia (AML). We report that the T/T(F) and T/T(L) fusion variants associated with congenital fibrosarcoma and AML, respectively, are cons...

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Vydáno v:EMBO J
Hlavní autoři: Liu, Qing, Schwaller, Juerg, Kutok, Jeffery, Cain, Danielle, Aster, Jon C., Williams, Ifor R., Gilliland, D.Gary
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2000
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302017/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10775267/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.8.1827
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