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Prevention of hyperglycemia-induced myocardial apoptosis by gene silencing of Toll-like receptor-4
BACKGROUND: Apoptosis is an early event involved in cardiomyopathy associated with diabetes mellitus. Toll-like receptor (TLR) signaling triggers cell apoptosis through multiple mechanisms. Up-regulation of TLR4 expression has been shown in diabetic mice. This study aimed to delineate the role of TL...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3020152/ https://ncbi.nlm.nih.gov/pubmed/21159162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-8-133 |
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