Prevention of hyperglycemia-induced myocardial apoptosis by gene silencing of Toll-like receptor-4

BACKGROUND: Apoptosis is an early event involved in cardiomyopathy associated with diabetes mellitus. Toll-like receptor (TLR) signaling triggers cell apoptosis through multiple mechanisms. Up-regulation of TLR4 expression has been shown in diabetic mice. This study aimed to delineate the role of TL...

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Hlavní autoři: Zhang, Yuwei, Peng, Tianqing, Zhu, Huaqing, Zheng, Xiufen, Zhang, Xusheng, Jiang, Nan, Cheng, Xiaoshu, Lai, Xiaoyan, Shunnar, Aminah, Singh, Manpreet, Riordan, Neil, Bogin, Vladimir, Tong, Nanwei, Min, Wei-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020152/
https://ncbi.nlm.nih.gov/pubmed/21159162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-8-133
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