Widespread transcription at neuronal activity-regulated enhancers

We used genome-wide sequencing methods to study stimulus-dependent enhancer function in neurons. We identified ∼12,000 neuronal activity-regulated enhancers that are bound by the general transcriptional co-activator CBP in an activity-dependent manner. A function of CBP at enhancers may be to recrui...

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Detalhes bibliográficos
Main Authors: Kim, Tae-Kyung, Hemberg, Martin, Gray, Jesse M., Costa, Allen M., Bear, Daniel M., Wu, Jing, Harmin, David A., Laptewicz, Mike, Barbara-Haley, Kellie, Kuersten, Scott, Markenscoff-Papadimitriou, Eirene, Kuhl, Dietmar, Bito, Haruhiko, Worley, Paul F., Kreiman, Gabriel, Greenberg, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020079/
https://ncbi.nlm.nih.gov/pubmed/20393465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09033
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