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Integrated genome analysis suggests that most conserved non-coding sequences are regulatory factor binding sites

More than 98% of a typical vertebrate genome does not code for proteins. Although non-coding regions are sprinkled with short (<200 bp) islands of evolutionarily conserved sequences, the function of most of these unannotated conserved islands remains unknown. One possibility is that unannotated c...

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Detalhes bibliográficos
Main Authors: Hemberg, Martin, Gray, Jesse M., Cloonan, Nicole, Kuersten, Scott, Grimmond, Sean, Greenberg, Michael E., Kreiman, Gabriel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439890/
https://ncbi.nlm.nih.gov/pubmed/22684627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks477
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