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Pseudomonas aeruginosa MucD Regulates the Alginate Pathway through Activation of MucA Degradation via MucP Proteolytic Activity
Alginate overproduction in Pseudomonas aeruginosa can be caused by the proteolysis of the anti-sigma factor MucA regulated by the AlgW protease. Here, we show that inactivation of MucD, an HtrA/DegP homolog and alginate regulator, can bypass AlgW, leading to an atypical proteolysis of MucA that is d...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3019965/ https://ncbi.nlm.nih.gov/pubmed/21036998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01132-10 |
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