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Pseudomonas aeruginosa MucD Regulates the Alginate Pathway through Activation of MucA Degradation via MucP Proteolytic Activity

Alginate overproduction in Pseudomonas aeruginosa can be caused by the proteolysis of the anti-sigma factor MucA regulated by the AlgW protease. Here, we show that inactivation of MucD, an HtrA/DegP homolog and alginate regulator, can bypass AlgW, leading to an atypical proteolysis of MucA that is d...

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Bibliografiske detaljer
Main Authors: Damron, F. Heath, Yu, Hongwei D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019965/
https://ncbi.nlm.nih.gov/pubmed/21036998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01132-10
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