Molecular basis of the lipid-induced MucA-MucB dissociation in Pseudomonas aeruginosa

MucA and MucB are critical negative modulators of sigma factor AlgU and regulate the mucoid conversion of Pseudomonas aeruginosa. Previous studies have revealed that lipid signals antagonize MucA-MucB binding. Here we report the crystal structure of MucB in complex with the periplasmic domain of Muc...

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Publicat a:Commun Biol
Autors principals: Li, Tao, He, Lihui, Li, Changcheng, Kang, Mei, Song, Yingjie, Zhu, Yibo, Shen, Yalin, Zhao, Ninglin, Zhao, Chang, Yang, Jing, Huang, Qin, Mou, Xingyu, Tong, Aiping, Yang, Jinliang, Wang, Zhenling, Ji, Chengjie, Li, Hong, Tang, Hong, Bao, Rui
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7400510/
https://ncbi.nlm.nih.gov/pubmed/32747658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01147-1
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