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The Pseudomonas aeruginosa Sensor Kinase KinB Negatively Controls Alginate Production through AlgW-Dependent MucA Proteolysis

Mucoidy, or overproduction of the exopolysaccharide known as alginate, in Pseudomonas aeruginosa is a poor prognosticator for lung infections in cystic fibrosis. Mutation of the anti-σ factor MucA is a well-accepted mechanism for mucoid conversion. However, certain clinical mucoid strains of P. aeru...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Damron, F. Heath, Qiu, Dongru, Yu, Hongwei D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655532/
https://ncbi.nlm.nih.gov/pubmed/19168621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01490-08
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