A carregar...

Biochemical determinants of 5-fluorouracil response in vivo. The role of deoxyuridylate pool expansion.

5-Fluorodeoxyuridine monophosphate (FdUMP), the active metabolite of 5-fluorouracil (5-FU), is a tight-binding inhibitor of thymidylate synthetase, the enzyme which converts dUMP to TMP. Newly developed assays for FdUMP and dUMP were utilized to assess the competitive roles played by these nucleotid...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Myers, C E, Young, R C, Chabner, B A
Formato: Artigo
Idioma:Inglês
Publicado em: 1975
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC301986/
https://ncbi.nlm.nih.gov/pubmed/1184747
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!