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Novel Compounds Containing Multiple Guanide Groups That Bind the HIV Coreceptor CXCR4
The G-protein-coupled receptor CXCR4 acts as a coreceptor for human immunodeficiency virus type 1 (HIV-1) infection, as well as being involved in signaling cell migration and proliferation. Compounds that block CXCR4 interactions have potential uses as HIV entry inhibitors to complement drugs such a...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3019677/ https://ncbi.nlm.nih.gov/pubmed/20937786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00709-10 |
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