Novel Compounds Containing Multiple Guanide Groups That Bind the HIV Coreceptor CXCR4

The G-protein-coupled receptor CXCR4 acts as a coreceptor for human immunodeficiency virus type 1 (HIV-1) infection, as well as being involved in signaling cell migration and proliferation. Compounds that block CXCR4 interactions have potential uses as HIV entry inhibitors to complement drugs such a...

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Detalhes bibliográficos
Main Authors: Wilkinson, Royce A., Pincus, Seth H., Shepard, Joyce B., Walton, Sarah K., Bergin, Edward P., Labib, Mohamed, Teintze, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019677/
https://ncbi.nlm.nih.gov/pubmed/20937786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00709-10
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