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Genetic Context and Biochemical Characterization of the IMP-18 Metallo-β-Lactamase Identified in a Pseudomonas aeruginosa Isolate from the United States

The production of metallo-β-lactamase (MBL) is an important mechanism of resistance to β-lactam antibiotics, including carbapenems. Despite the discovery and emergence of many acquired metallo-β-lactamases, IMP-type determinants (now counting at least 27 variants) remain the most prevalent in some g...

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Détails bibliographiques
Auteurs principaux: Borgianni, Luisa, Prandi, Silvia, Salden, Laurie, Santella, Gisela, Hanson, Nancy D., Rossolini, Gian Maria, Docquier, Jean-Denis
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019669/
https://ncbi.nlm.nih.gov/pubmed/21041509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00858-10
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