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Amiodarone Inhibits Trypanosoma cruzi Infection and Promotes Cardiac Cell Recovery with Gap Junction and Cytoskeleton Reassembly In Vitro

We present the results of the first detailed study of the antiproliferative and ultrastructural effects of amiodarone on Trypanosoma cruzi, the causative agent of Chagas' disease. Moreover, we report the effects of this compound on the recovery of F-actin fibrils, connexin43, and contractility...

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Detalles Bibliográficos
Main Authors: Adesse, Daniel, Meirelles Azzam, Eduardo, de Nazareth L. Meirelles, Maria, Urbina, Julio A., Garzoni, Luciana R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019665/
https://ncbi.nlm.nih.gov/pubmed/21078932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01129-10
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