DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans

DC-SIGN, a C-type lectin expressed on the surface of dendritic cells (DCs), efficiently binds and transmits HIVs and simian immunodeficiency viruses to susceptible cells in trans. A DC-SIGN homologue, termed DC-SIGNR, has recently been described. Herein we show that DC-SIGNR, like DC-SIGN, can bind...

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Bibliografiske detaljer
Main Authors: Pöhlmann, Stefan, Soilleux, Elizabeth J., Baribaud, Frédéric, Leslie, George J., Morris, Lesley S., Trowsdale, John, Lee, Benhur, Coleman, Nicholas, Doms, Robert W.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC30196/
https://ncbi.nlm.nih.gov/pubmed/11226297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051631398
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