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DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans

DC-SIGN, a C-type lectin expressed on the surface of dendritic cells (DCs), efficiently binds and transmits HIVs and simian immunodeficiency viruses to susceptible cells in trans. A DC-SIGN homologue, termed DC-SIGNR, has recently been described. Herein we show that DC-SIGNR, like DC-SIGN, can bind...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Pöhlmann, Stefan, Soilleux, Elizabeth J., Baribaud, Frédéric, Leslie, George J., Morris, Lesley S., Trowsdale, John, Lee, Benhur, Coleman, Nicholas, Doms, Robert W.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30196/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11226297/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.051631398
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