DC-SIGN Interactions with Human Immunodeficiency Virus: Virus Binding and Transfer Are Dissociable Functions

The C-type lectins DC-SIGN and DC-SIGNR capture and transfer human immunodeficiency virus (HIV) to susceptible cells, although the underlying mechanism is unclear. Here we show that DC-SIGN/DC-SIGNR-mediated HIV transmission involves dissociable binding and transfer steps, indicating that efficient...

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Autores principales: Pöhlmann, Stefan, Leslie, George J., Edwards, Terri G., Macfarlan, Todd, Reeves, Jacqueline D., Hiebenthal-Millow, Kirsten, Kirchhoff, Frank, Baribaud, Frédéric, Doms, Robert W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC114631/
https://ncbi.nlm.nih.gov/pubmed/11581425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.21.10523-10526.2001
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