DC-SIGN Interactions with Human Immunodeficiency Virus: Virus Binding and Transfer Are Dissociable Functions

The C-type lectins DC-SIGN and DC-SIGNR capture and transfer human immunodeficiency virus (HIV) to susceptible cells, although the underlying mechanism is unclear. Here we show that DC-SIGN/DC-SIGNR-mediated HIV transmission involves dissociable binding and transfer steps, indicating that efficient...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Pöhlmann, Stefan, Leslie, George J., Edwards, Terri G., Macfarlan, Todd, Reeves, Jacqueline D., Hiebenthal-Millow, Kirsten, Kirchhoff, Frank, Baribaud, Frédéric, Doms, Robert W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114631/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11581425/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.21.10523-10526.2001
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