Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis

UDP-glucuronosyltransferases (UGTs) play an important role in the metabolism and excretion of various endogenous and xenobiotic compounds, including carcinogens and chemotherapeutic agents. The goal of the present study was to examine UGT2A1 expression in human tissues, determine its glucuronidation...

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Hlavní autoři: Bushey, Ryan T., Chen, Gang, Blevins-Primeau, Andrea S., Krzeminski, Jacek, Amin, Shantu, Lazarus, Philip
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019304/
https://ncbi.nlm.nih.gov/pubmed/21164388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328341db05
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