Pioglitazone attenuates mitochondrial dysfunction, cognitive impairment, cortical tissue loss, and inflammation following traumatic brain injury

Following traumatic brain injury (TBI) there is significant neuropathology which includes mitochondrial dysfunction, loss of cortical grey matter, microglial activation, and cognitive impairment. Previous evidence has shown that activation of the peroxisome proliferator-activated receptors (PPARs) p...

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Hlavní autoři: Sauerbeck, Andrew, Gao, Jianxin, Readnower, Ryan, Liu, Mei, Pauly, James R, Bing, Guoying, Sullivan, Patrick
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019268/
https://ncbi.nlm.nih.gov/pubmed/20965168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2010.10.003
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