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Pregnane X receptor-mediated induction of Cyp3a by black cohosh

Black cohosh (BC) has been widely applied for the treatment of menopausal symptoms. However, increasing concerns about herb-drug interactions demand the need for studies on the influence of BC on cytochromes 450. Cyp3a11 in liver was induced by 7-fold in wild-type mice treated with 500mg/kg black co...

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Bibliographic Details
Main Authors: Pang, Xiaoyan, Cheng, Jie, Krausz, Kristopher W., Guo, De-an, Gonzalez, Frank J.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019262/
https://ncbi.nlm.nih.gov/pubmed/20979450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2010.527021
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