Nalaganje...
Alterations of Histone Modifications Contribute to Pregnane X Receptor-Mediated Induction of CYP3A4 by Rifampicin
CYP3A4 is one of the major drug-metabolizing enzymes in human and is responsible for the metabolism of 60% of clinically used drugs. Many drugs are able to induce the expression of CYP3A4, which usually causes drug-drug interactions and adverse drug reactions. This study aims to explore the role of...
Shranjeno v:
| izdano v: | Mol Pharmacol |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Pharmacology and Experimental Therapeutics
2017
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5508193/ https://ncbi.nlm.nih.gov/pubmed/28546420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.108225 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|