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SVM classifier to predict genes important for self-renewal and pluripotency of mouse embryonic stem cells

BACKGROUND: Mouse embryonic stem cells (mESCs) are derived from the inner cell mass of a developing blastocyst and can be cultured indefinitely in-vitro. Their distinct features are their ability to self-renew and to differentiate to all adult cell types. Genes that maintain mESCs self-renewal and p...

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Autori principali: Xu, Huilei, Lemischka, Ihor R, Ma'ayan, Avi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019180/
https://ncbi.nlm.nih.gov/pubmed/21176149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-4-173
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