Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers

BACKGROUND: Age-related neurodegenerative diseases share a number of important pathological features, such as accumulation of misfolded proteins as amyloid oligomers and fibrils. Recent evidence suggests that soluble amyloid oligomers and not the insoluble amyloid fibrils may represent the primary p...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kayed, Rakez, Canto, Isabel, Breydo, Leonid, Rasool, Suhail, Lukacsovich , Tamas, Wu, Jessica, Albay, Ricardo, Pensalfini, Anna, Yeung, Stephen, Head, Elizabeth, Marsh, J Lawrence, Glabe, Charles
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019145/
https://ncbi.nlm.nih.gov/pubmed/21144050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-57
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