Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers

BACKGROUND: Age-related neurodegenerative diseases share a number of important pathological features, such as accumulation of misfolded proteins as amyloid oligomers and fibrils. Recent evidence suggests that soluble amyloid oligomers and not the insoluble amyloid fibrils may represent the primary p...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Kayed, Rakez, Canto, Isabel, Breydo, Leonid, Rasool, Suhail, Lukacsovich , Tamas, Wu, Jessica, Albay, Ricardo, Pensalfini, Anna, Yeung, Stephen, Head, Elizabeth, Marsh, J Lawrence, Glabe, Charles
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2010
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019145/
https://ncbi.nlm.nih.gov/pubmed/21144050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-57
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