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CRITICAL AGE-RELATED LOSS OF COFACTORS OF NEURON CYTOCHROME C OXIDASE REVERSED BY ESTROGEN
The mechanistic basis for the correlation between mitochondrial dysfunction and neurodegenerative disease is unclear, but evidence supports involvement of cytochrome C oxidase (CCO) deficits with age. Neurons isolated from the brains of 24 month and 9 month rats and cultured in common conditions pro...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018880/ https://ncbi.nlm.nih.gov/pubmed/18930048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2008.09.011 |
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