CRITICAL AGE-RELATED LOSS OF COFACTORS OF NEURON CYTOCHROME C OXIDASE REVERSED BY ESTROGEN

The mechanistic basis for the correlation between mitochondrial dysfunction and neurodegenerative disease is unclear, but evidence supports involvement of cytochrome C oxidase (CCO) deficits with age. Neurons isolated from the brains of 24 month and 9 month rats and cultured in common conditions pro...

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Bibliographic Details
Main Authors: Jones, Torrie T., Brewer, Gregory J.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018880/
https://ncbi.nlm.nih.gov/pubmed/18930048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2008.09.011
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