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Age-related deficiencies in complex I endogenous substrate availability and reserve capacity of complex IV in cortical neuron electron transport

Respiratory enzyme complex dysfunction is mechanistically involved in mitochondrial failure leading to neurodegenerative disease, but the pathway is unclear. Here, age-related differences in mitochondrial respiration were measured in both whole and permeabilized neurons from 9-month and 24-month adu...

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Autors principals: Jones, Torrie T., Brewer, Gregory J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812684/
https://ncbi.nlm.nih.gov/pubmed/19799853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2009.09.009
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