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Age-related deficiencies in complex I endogenous substrate availability and reserve capacity of complex IV in cortical neuron electron transport

Respiratory enzyme complex dysfunction is mechanistically involved in mitochondrial failure leading to neurodegenerative disease, but the pathway is unclear. Here, age-related differences in mitochondrial respiration were measured in both whole and permeabilized neurons from 9-month and 24-month adu...

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Detalhes bibliográficos
Main Authors: Jones, Torrie T., Brewer, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812684/
https://ncbi.nlm.nih.gov/pubmed/19799853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2009.09.009
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