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Analyzing marginal cases in differential shotgun proteomics

Summary: We present an approach to statistically pinpoint differentially expressed proteins that have quantitation values near the quantitation threshold and are not identified in all replicates (marginal cases). Our method uses a Bayesian strategy to combine parametric statistics with an empirical...

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Detalhes bibliográficos
Main Authors: Carvalho, Paulo C., Fischer, Juliana S. G., Perales, Jonas, Yates, John R., Barbosa, Valmir C., Bareinboim, Elias
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018820/
https://ncbi.nlm.nih.gov/pubmed/21075743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq632
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