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Improving the TFold test for differential shotgun proteomics

Summary: We present an updated version of the TFold software for pinpointing differentially expressed proteins in shotgun proteomics experiments. Given an FDR bound, the updated approach uses a theoretical FDR estimator to maximize the number of identifications that satisfy both a fold-change cutoff...

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Detalhes bibliográficos
Main Authors: Carvalho, Paulo C., Yates, John R., Barbosa, Valmir C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371870/
https://ncbi.nlm.nih.gov/pubmed/22539673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts247
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