Inhibition of human platelet aggregation by monovalent antifibrinogen antibody fragments.

Monovalent goat antibody fragments (Fab) that were monospecific for human fibrinogen were isolated by affinity chromatography on fibrinogen-Sepharose and used as a direct probe for the involvement of fibrinogen in platelet aggregation and the release reaction. The antifibrinogen Fab inhibited aggreg...

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Pubblicato in:	J Clin Invest
Autori principali:	Tollefsen, D M, Majerus, P W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1975
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301881/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1169259/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108045
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