C/EBPδ: friend or foe? A novel role for C/EBPδ in metastasis

This issue of The EMBO Journal features opposing functions of the assumed tumour suppressor C/EBPδ shown here to promote tumour metastasis. Mechanistically, C/EBPδ amplifies HIF-1α signalling, thus integrating hypoxic inflammation with tumour metastasis.

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Main Authors: Pelorosso, Facundo G, Balmain, Allan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
Teme:
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018802/
https://ncbi.nlm.nih.gov/pubmed/21157479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.308
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