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EVALUATION OF THIOL-BASED ANTIOXIDANT THERAPEUTICS IN CYSTIC FIBROSIS SPUTUM: FOCUS ON MYELOPEROXIDASE
Neutrophil-dependent reactions catalyzed by myeloperoxidase (MPO) are thought to play important roles in the pulmonary pathobiology of cystic fibrosis (CF). Aerosolized thiol antioxidants such as glutathione (GSH) and N-acetylcysteine (NAC) are currently being utilized as therapeutics to modify CF r...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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2010
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018684/ https://ncbi.nlm.nih.gov/pubmed/20954832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10715762.2010.521154 |
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