EVALUATION OF THIOL-BASED ANTIOXIDANT THERAPEUTICS IN CYSTIC FIBROSIS SPUTUM: FOCUS ON MYELOPEROXIDASE

Neutrophil-dependent reactions catalyzed by myeloperoxidase (MPO) are thought to play important roles in the pulmonary pathobiology of cystic fibrosis (CF). Aerosolized thiol antioxidants such as glutathione (GSH) and N-acetylcysteine (NAC) are currently being utilized as therapeutics to modify CF r...

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Detalhes bibliográficos
Main Authors: Vasu, Vihas T., De Cruz, Sharon J., Houghton, Jessica S., Hayakawa, Keri A., Morrissey, Brian M., Cross, Carroll E., Eiserich, Jason P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018684/
https://ncbi.nlm.nih.gov/pubmed/20954832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10715762.2010.521154
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