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Uptake and Metabolism of the Novel Peptide Angiotensin-(1-12) by Neonatal Cardiac Myocytes

BACKGROUND: Angiotensin-(1–12) [Ang-(1–12)] functions as an endogenous substrate for the productions of Ang II and Ang-(1–7) by a non-renin dependent mechanism. This study evaluated whether Ang-(1–12) is incorporated by neonatal cardiac myocytes and the enzymatic pathways of (125)I-Ang-(1–12) metabo...

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Bibliografiske detaljer
Main Authors: Ahmad, Sarfaraz, Varagic, Jasmina, Westwood, Brian M., Chappell, Mark C., Ferrario, Carlos M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018413/
https://ncbi.nlm.nih.gov/pubmed/21249217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015759
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