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Defining Genetic Factors That Modulate Intergenerational CAG Repeat Instability in Drosophila melanogaster
Trinucleotide repeat instability underlies >20 human hereditary disorders. These diseases include many neurological and neurodegenerative situations, such as those caused by pathogenic polyglutamine (polyQ) domains encoded by expanded CAG repeats. Although mechanisms of instability have been inte...
में बचाया:
| मुख्य लेखकों: | , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Genetics Society of America
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018324/ https://ncbi.nlm.nih.gov/pubmed/21041558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.121418 |
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