Nonsense-mediated decay targets have multiple sequence-related features that can inhibit translation

Nonsense-mediated mRNA decay (NMD) is a surveillance system that eliminates transcripts with premature termination codons. In this study, we show that mRNAs targeted by NMD are also suppressed at the translational level. The low translational efficiency (TE) is a consequence of multiple features act...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Zhang, Zhenguo, Zhou, Li, Hu, Landian, Zhu, Yufei, Xu, Heng, Liu, Yang, Chen, Xianfen, Yi, Xianfu, Kong, Xiangyin, Hurst, Laurence D
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2010
נושאים:
Report
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018160/
https://ncbi.nlm.nih.gov/pubmed/21179015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.101
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים