Genes That Escape X-Inactivation in Humans Have High Intraspecific Variability in Expression, Are Associated with Mental Impairment but Are Not Slow Evolving

In female mammals most X-linked genes are subject to X-inactivation. However, in humans some X-linked genes escape silencing, these escapees being candidates for the phenotypic aberrations seen in polyX karyotypes. These escape genes have been reported to be under stronger purifying selection than o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhang, Yuchao, Castillo-Morales, Atahualpa, Jiang, Min, Zhu, Yufei, Hu, Landian, Urrutia, Araxi O., Kong, Xiangyin, Hurst, Laurence D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Discoveries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840307/
https://ncbi.nlm.nih.gov/pubmed/24023392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mst148
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados