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Impaired survival of T helper cells in the absence of CD4

Signal transduction in response to ligand recognition by T cell receptors regulates T cell fate within and beyond the thymus. Herein we examine the involvement of the CD4 molecule in the regulation of T helper cell survival. T helper cells that lack CD4 expression are prone to apoptosis and show dim...

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Autori principali: Strong, Julie, Wang, Qi, Killeen, Nigel
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC30178/
https://ncbi.nlm.nih.gov/pubmed/11226279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051329698
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