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Biochemical and structural characterization of β-catenin interactions with non-phosphorylated and CK2-phosphorylated Lef-1
In the Wnt/β-catenin signaling pathway, β-catenin activates target genes through its interactions with the TCF/Lef family of transcription factors. The crystal structures of complexes between the β-catenin armadillo domain and the Lef-1 N-terminal domain show that the overall conformation and many o...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3017643/ https://ncbi.nlm.nih.gov/pubmed/21075118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.11.010 |
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