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A conserved phosphorylation switch controls the interaction between cadherin and β-catenin in vitro and in vivo
In metazoan adherens junctions, β-catenin links the cytoplasmic tail of classical cadherins to the F-actin-binding protein α-catenin. Phosphorylation of a Ser/Thr rich region in the cadherin tail dramatically enhances affinity for β-catenin and promotes cell-cell adhesion in cell culture systems, bu...
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| Publicado no: | Dev Cell |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4390766/ https://ncbi.nlm.nih.gov/pubmed/25850673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.02.005 |
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