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Natural and engineered nicking endonucleases—from cleavage mechanism to engineering of strand-specificity

Restriction endonucleases (REases) are highly specific DNA scissors that have facilitated the development of modern molecular biology. Intensive studies of double strand (ds) cleavage activity of Type IIP REases, which recognize 4–8 bp palindromic sequences, have revealed a variety of mechanisms of...

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מידע ביבליוגרפי
Main Authors: Chan, Siu-Hong, Stoddard, Barry L., Xu, Shuang-yong
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017599/
https://ncbi.nlm.nih.gov/pubmed/20805246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq742
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