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VSV Oncolytic Virotherapy in the B16 Model Depends Upon Intact MyD88 Signaling

We show here, for the first time to our knowledge, that the antitumor therapy of oncolytic vesicular stomatitis virus (VSV) in the B16ova model depends upon signaling through myeloid differentiation primary response gene 88 (MyD88) in host cells. VSV-mediated therapy of B16ova tumors was abolished i...

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Detalhes bibliográficos
Main Authors: Wongthida, Phonphimon, Diaz, Rosa M, Galivo, Feorillo, Kottke, Timothy, Thompson, Jill, Melcher, Alan, Vile, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017452/
https://ncbi.nlm.nih.gov/pubmed/20959810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.225
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