Systemic Administration of Ribbon-type Decoy Oligodeoxynucleotide Against Nuclear Factor κB and Ets Prevents Abdominal Aortic Aneurysm in Rat Model

Currently, there is no effective clinical treatment to prevent abdominal aortic aneurysm (AAA). To develop a novel therapeutic approach, we modified decoy oligodeoxynucleotide (ODN) against nuclear factor κB (NFκB) and ets, to a ribbon-shaped circular structure without chemical modification, to incr...

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Detaylı Bibliyografya
Asıl Yazarlar: Miyake, Takashi, Aoki, Motokuni, Osako, Mariana K, Shimamura, Munehisa, Nakagami, Hironori, Morishita, Ryuichi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2011
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017441/
https://ncbi.nlm.nih.gov/pubmed/20877343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.208
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