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Systemic Administration of Ribbon-type Decoy Oligodeoxynucleotide Against Nuclear Factor κB and Ets Prevents Abdominal Aortic Aneurysm in Rat Model

Currently, there is no effective clinical treatment to prevent abdominal aortic aneurysm (AAA). To develop a novel therapeutic approach, we modified decoy oligodeoxynucleotide (ODN) against nuclear factor κB (NFκB) and ets, to a ribbon-shaped circular structure without chemical modification, to incr...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Miyake, Takashi, Aoki, Motokuni, Osako, Mariana K, Shimamura, Munehisa, Nakagami, Hironori, Morishita, Ryuichi
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017441/
https://ncbi.nlm.nih.gov/pubmed/20877343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.208
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