Systemic Administration of Ribbon-type Decoy Oligodeoxynucleotide Against Nuclear Factor κB and Ets Prevents Abdominal Aortic Aneurysm in Rat Model

Currently, there is no effective clinical treatment to prevent abdominal aortic aneurysm (AAA). To develop a novel therapeutic approach, we modified decoy oligodeoxynucleotide (ODN) against nuclear factor κB (NFκB) and ets, to a ribbon-shaped circular structure without chemical modification, to incr...

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Bibliografiske detaljer
Main Authors: Miyake, Takashi, Aoki, Motokuni, Osako, Mariana K, Shimamura, Munehisa, Nakagami, Hironori, Morishita, Ryuichi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017441/
https://ncbi.nlm.nih.gov/pubmed/20877343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.208
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