Methotrexate ameliorates pristane-induced arthritis by decreasing IFN-γ and IL-17A expressions

Objective: This study was carried out to test the effects of methotrexate (MTX) and black seed oil (BSO) on pristane-induced arthritis (PIA) in rats. Methods: Inbred dark agouti (DA) rats were induced by a single subcutaneous injection of pristane, and then treated with MTX or BSO. Arthritis severit...

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Главные авторы: Hou, Wei-kun, Meng, Lie-su, Zheng, Fang, Wen, Yu-rong, Zhu, Wen-hua, Jiang, Cong-shan, He, Xiao-jing, Zhou, Yan, Lu, She-min
Формат: Artigo
Язык:Inglês
Опубликовано: Zhejiang University Press 2011
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017415/
https://ncbi.nlm.nih.gov/pubmed/21194185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1000078
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