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Estrogen increases, whereas IL-27 and IFN-γ decrease, splenocyte IL-17 production in wild type mice

Estrogen-mediated regulation of Th1, Th2 and Treg effector functions are well documented but, surprisingly, it is still not known whether estrogen modulates IL-17, a powerful proinflammatory cytokine that plays a pivotal role in several inflammatory and autoimmune diseases. Therefore in the present...

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Autori principali: Khan, Deena, Dai, Rujuan, Karpuzoglu, Ebru, Ahmed, S Ansar
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097107/
https://ncbi.nlm.nih.gov/pubmed/20623549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040303
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