Propylthiouracil blocks extrathyroidal conversion of thyroxine to triiodothyronine and augments thyrotropin secretion in man.

Propylthiouracil (PTU) inhibits peripheral deiodination of thyroxine (T4) and triiodothyronine (T3) and decreases the metabolic effectiveness of T4 in animals. To assess the effect of PTU on extrathyroidal conversion of T4 to T3 in man, 15 studies were performed in athyreotic patients treated with 1...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Geffner, D L, Azukizawa, M, Hershman, J M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1975
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/805160/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107925
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