Propylthiouracil blocks extrathyroidal conversion of thyroxine to triiodothyronine and augments thyrotropin secretion in man.

Propylthiouracil (PTU) inhibits peripheral deiodination of thyroxine (T4) and triiodothyronine (T3) and decreases the metabolic effectiveness of T4 in animals. To assess the effect of PTU on extrathyroidal conversion of T4 to T3 in man, 15 studies were performed in athyreotic patients treated with 1...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Geffner, D L, Azukizawa, M, Hershman, J M
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1975
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/805160/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107925
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