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The Distribution and Expression of Picalm in Alzheimer Disease

PICALM, the gene encoding phosphatidylinositol-binding clathrin assembly (picalm) protein, was recently shown to be associated with risk of Alzheimer disease (AD). Picalm is a key component of clathrin-mediated endocytosis. It recruits clathrin and adaptor protein (AP)-2 to the plasma membrane and a...

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Detalhes bibliográficos
Main Authors: Baig, Shabnam, Joseph, Sally A., Tayler, Hannah, Abraham, Richard, Owen, Michael J., Williams, Julie, Kehoe, Patrick G., Love, Seth
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017341/
https://ncbi.nlm.nih.gov/pubmed/20838239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e3181f52e01
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