Angiotensin-converting enzyme levels and activity in Alzheimer's disease: differences in brain and CSF ACE and association with ACE1 genotypes

Angiotensin-converting enzyme (ACE) has been implicated in Alzheimer's disease (AD): ACE1 variations influence plasma ACE and risk of AD, and ACE is increased in AD brain. We measured frontal ACE level and activity in 89 AD and 51 control brains, and post-mortem CSF from 101 cases and 19 contro...

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Detalhes bibliográficos
Main Authors: Miners, Scott, Ashby, Emma, Baig, Shabnam, Harrison, Rachel, Tayler, Hannah, Speedy, Elizabeth, Prince, Jonathan A, Love, Seth, Kehoe, Patrick G
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776311/
https://ncbi.nlm.nih.gov/pubmed/19956428
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